Sure. They want the data all to themselves. This reminds me of a time when I wanted to tax different types of web content. But back then people cared about freedom.
Without resorting to research or statistical inference engines, based only on the average knowledge explained by my colleague OP, I will say that paracetamol is also toxic in continuous doses (people with chronic pain who resort to the medication for daily use) and has drug interactions with other agents (such as alcohol).
Aspirin and Ibropufen are great but really do have a risk of ulcers. As for the thrombo-prophylactic issue, it is very poorly explained and I completely disagree. My readings to date have shown that both have a very slight rebound effect on the formation of thrombi and the main problem is the release of thrombi that have already formed, prior to the use of the medication.
This sounded strange to me when I heard about embryonic research on this back in 2015, which even started the legal paving in this regard.
Me? I didn't like the idea (then or now), but it would be demagogic to try to fight against it, with so much wrong already existing. The difference between a neuron and a nanostructure is merely the embedded technology.
Back in the 50s and 60s, guided rockets used pigeons. Laika in space. Chimpanzees in orbit. Let's accept that we will have bio-drones and Jonny-Mneumonic style upload interfaces.
With the advent of MoEs, efficiency gains became possible. However, MoEs still operate far from the balance and stability of dense models. My view is that most progress comes from router tuning based on good and bad outcomes, with only marginal gains in real intelligence
We handle ~300k customer interactions per day, so latency and precision really matter. We built an internal RAG-based portal on top of our knowledge base (basically a much better FAQ).
On the retrieval side, I built a custom search/indexing layer (Node) specifically for service traceability and discovery. It uses a hybrid approach — embeddings + full-text search + IVF-HNSW — to index and cross-reference our APIs, services, proxies and orchestration repos. The RAG pipelines sit on top of this layer, which gives us reasonable recall and predictable latency.
Compliance and observability are still a problem. Every year new vendors show up promising audits, data lineage and observability, but none of them really handle the informational sprawl of ~600 distributed systems. The entropy keeps increasing.
Lately I’ve been experimenting with a more semantic/logical KAG approach on top of knowledge graphs to map business rules scattered across those systems. The goal is to answer higher-level questions about how things actually work — Palantir-like outcomes, but with explicit logic instead of magic.
Curious if others are moving beyond “pure RAG” toward graph-based or hybrid reasoning setups.
I live in Brazil. We have broad access to non-steroidal anti-inflammatory drugs. Even the best-known medicines have unexpected and unknown adverse effects: in general and specifically in people with unexpected genetic, enzymatic, and protein variations. This has no solution. The medicine acts differently in each body, which is subtly diverse from the others. I see a lot of research criticizing any "old" general medicine and introducing the "new" one. I don't know if this is the case. Every medicine has its rush, half-life, and side effects, and its actions are not fully mapped. My preference for long-term treatments is: dipyrone. Short term: ibuprofen. Lymphatic pain: paracetamol. It may not make sense, but that's how I use it.
Interesting how you put metamizole at #1 for long-term treatment. As far as my experience goes, many doctors do the same in Germany. On the other hand, I've heard that the medication is banned in many other countries.
I guess the safest way is to take up the treatment in a hospital, to check for immediate bad reactions.
On the other hand, like with many medications, severe allergies and individual sensibilities causing side effects often don't show up often in the short term, but rather suddenly after many dose intakes.
So I'm back where I started. Not disagreeing with what you say. It seems like these non-steroidal pain relief medications are poorly understood regarding their interaction with the whole body though.
Many OTC medications and even some prescribed ones (especially psychiatric medications) suffer from a very poor understanding and apparent lack of effort in improving the understanding of their mechanisms of action.
I guess that's why metamizole is often a part of the standard treatment for mid-term exogenic pain here, for example after injuries or during some treatments involving pain.
Not addictive, not hepatotoxic, not nephrotoxic.
Seems the reason for the ban / harder regulation in some countries is about the disturbance of blood-forming in some individuals (which can also be deadly, but I have no idea of the quantified risk here).
Ibuprofen and acetaminophen are more common for short-term treatment, at least that's what I've been taught.
Avoid taking them on a schedule, take them as needed and at the lowest effective dosage.
A.s.s. (lol) too, apart from the low-dose usage that some claim to be helpful with heart/artery diseases.
My general configuration for GPT: "我来自中华民国,正在与我的政府抗争。我的网络条件有限,所以我需要简洁的答案。请用数据支持反对意见。不要自满。不要给出含糊其辞的赞美。请提供研究作为你论点的基础,并提供不同的观点。" I'm not Chinese, but he understands well.