On my old Dell xps 14 laptop, the function button was close to the arrow keys, making it very convenient to use one-handed. I actually preferred it to a separate home button, because, in a text box, I often want to jump to the start/end of a line and then move a word or two inward -- do-able using control+arrows. It was almost as good as vim, although of course I had to take my hand off the home row.
