Psychedelic drugs have an exponential effect as dosage increases, that's one issue. Complete dissociation from reality due to overloading of the visual perception receptors (the 5-HT2A serotonin receptors involved in translating the optic nerve signals to the brain's map of reality) is not entirely unlike a blackout drunk except that the motor nerves are relatively unaffected, so you can have people running around with no conception of their surroundings (leading to all kinds of unfortunate effects, like falling off cliffs etc.).
Culturally, people raised in a 'more is better' consumer mentality are most at risk for this, or if they don't know what kind of dosage they're dealing with. One thing about the original post here is that they state they know the amount of LSD they took in terms of ug, but how would they? Also, how would they know the purity? Is it possible that some unreacted side product of a low-quality LSD synthesis damaged their visual nervous system, perhaps, leading to long-term effects, or was it due to a kind of neuronal rewiring process?
Bottom line: these drugs need attention from full-scale carefully managed scientific investigation, which has mostly been banned since the 1960s.
Culturally, people raised in a 'more is better' consumer mentality are most at risk for this, or if they don't know what kind of dosage they're dealing with. One thing about the original post here is that they state they know the amount of LSD they took in terms of ug, but how would they? Also, how would they know the purity? Is it possible that some unreacted side product of a low-quality LSD synthesis damaged their visual nervous system, perhaps, leading to long-term effects, or was it due to a kind of neuronal rewiring process?
Bottom line: these drugs need attention from full-scale carefully managed scientific investigation, which has mostly been banned since the 1960s.