If you are currently or were recently on SSRI antidepressants, there is a danger of triggering serotonin syndrome from LSD or psilocybin.
> Some recreational drugs, such as LSD and cocaine, and dietary supplements, including St. John's wort and ginseng, can also cause serotonin syndrome when you take them with these antidepressants.
> Some recreational drugs, such as LSD and cocaine, and dietary supplements, including St. John's wort and ginseng, can also cause serotonin syndrome when you take them with these antidepressants.
https://www.webmd.com/depression/guide/serotonin-syndrome-ca...