I keep thinking back on a space opera conflict involving many domains of species. There are mammalian, avian, reptile, etc. They've formed coalitions in an effort to catch some highly valuable fugitive humans. (IIRC from Brin's Uplift Wars universe. Star Tide Rising?)

The machine's weapons of choice are algorithms, code, simulations, viruses. No physical violence. But still very high stakes, like mind wipes.