No, you can't. There's no usable desktop software that you can run there. Artificial restrictions will stay, although might be slightly relaxed. In contrast with Librem 5 running GNU/Linux (my daily driver) this is already a reality.
I don't think so, this has always been the limitation and why things like Windows ARM and Windows Phone fail over and over again. The interface part is easy, I guess, the application part is not. If you can figure out the application part, then you have a real shot at disrupting the market.
So far, only Apple has figured out the applications part on MacOS, and only partially. They still have wierdo iPadOS. Microsoft is doing Windows on ARM... again. We'll see how long that lasts.