> I totally agree with the author that the tickets we're assigned are all puzzles that I could lose myself in and inevitably get some feeling of satisfaction when I figure it out. But in the grand scheme of things, most of us aren't working on problems of real significance (eg. curing cancer, creating a more efficient battery).

So what? Most people aren't curing cancer, or doing anything more of value than their paycheck reflects. And maybe the value of our paycheck is really inflated, even. In the end we are just floating on a giant ~ball through space and maybe someday we'll have a cataclysmic event that undoes all of our social and scientific progress. Stop thinking that you have to be some special snowflake, relax, and maybe you'll find that you can find pleasure in the little, mundane stuff. In the end, they're all we really have.